About Ketamine

What is Ketamine?


Ketamine is well known drug that has been used as an anesthetic for over 50 years, is used in operating rooms around the world, and is viewed by World Health Organization as core medicine in healthcare. The FDA has approved it as an anesthetic, and anesthesiologists use it routinely for this purpose. While low dose ketamine has not been FDA approved for the treatment of Chronic Pain, Depression, Anxiety, Diabetic Peripheral Neuropathy (nerve pain), Inflammatory Pain, Fibromyalgia, Bipolar Disorder or Post Traumatic Stress Disorder (PTSD); and other diseases, researchers for the last 15 years have shown that sub-clinical doses can rapidly relieve symptoms when given as IV infusions. Studies confirming benefits have been done at Yale University, the National Institute of Health, Harvard University, Johns Hopkins, and others. Our physicians customize treatment plans for each patient and have accentuated this by creating RESET Ketamine Therapy™, which includes five distinct proprietary ketamine formulations: KalyCalm™, KalyCan™, KalyMax™, KalyPro™ and KalyZen™.



How Does Ketamine Work?


Ketamine inhibits NMDA receptors in the body. These receptors are responsible for central sensitization. Ketamine infusions work in a completely different way from any medication you may have tried before. Narcotics, anxiolytics, and anti-depression medication all work by trying to "block" certain pathways, but do not actually work to improve the problem. Ketamine essentially "re-sets" neural pathways and triggers a rapid growth of neural connections. It is also a powerful anti-inflammatory agent which helps many patients as well. While research is ongoing, and more precise mechanisms may be identified for this off-label use, the data to date has shown up to 70% of patients receive relief of their symptoms after one infusion. Additionally, patients that undergo the recommended treatment of 4-6 infusions over a 2-3 week period receive 90-95% relief. In some cases, maintenance infusions may be needed every 3-6 months.



Explore additional frequently asked questions about Ketamine and check out our Ketamine Clinical Library




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